The creators of The Matrix offered the role of Neo (which they were going to rewrite for a woman) to Sandra Bullock. But she wasn't interested in the script.
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Britney Spears was one of the actresses who was considered for the part in The Notebook. She even auditioned with Gosling.
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Breaking Bad creator Vince Gilligan wanted Bryan Cranston to play the iconic Walter White. However, AMC wanted a famous celebrity to star in the series. So, they offered Matthew Broderick the role but he turned it down.
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Jennifer Lawrence admitted that she auditioned for the lead in Easy A and said she really wanted it, but of course, the role went to Emma Stone.
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Christopher Plummer can’t recall the exact reason why he turned down the role of Gandalf in Lord of the Rings.
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Halle Berry could’ve starred in the hit spy series Homeland, but they ultimately went with Claire Danes who had just won a bunch of awards for her role in the Temple Grandin.
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Eric Stoltz lost the part of Marty McFly in Back to the Future in the middle of shooting, because the creators didn’t feel that he was good enough in the comedy scenes.
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The studio wanted Cher to play Morticia in The Addams Family, but the director insisted that the movie be balanced and not built around one celebrity.
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Elizabeth Banks wanted the role of Mary-Jane in the first Spider-Man movie, opposite Tobey Maguire, but says "I was told that I was too old to play her, even though Tobey and I were basically the same age."
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Benedict Cumberbatch auditioned for the lead role in the True Blood series, but Stephen Moyer got the part.
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Renée Zellweger could have gotten the main part in 13 Going on 30 but in the end, Jennifer Garner got it.
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Director Cameron Crowe originally wrote the script of Jerry Maguire imagining Tom Hanks in the main role. However, by the time shooting had started, too much time had passed and the actor aged out of the role.
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Claire Danes turned down the role in Titanic because after the film Romeo + Juliet that she appeared in with DiCaprio, she was no longer very interested in romantic roles.
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Dwayne “The Rock” Johnson says he "went after the role of Jack Reacher, but Cruise got it."
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Kate Hudson was supposed to play the role of Kat in the cult youth movie 10 Things I Hate About You. However, her mother, actress Goldie Hawn, didn’t like the script and persuaded her to refuse the role.
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The president of NBC recommended Paul Giamatti for the iconic role of Michael Scott in The Office, but the actor turned it down and it went to Steve Carell instead.
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Reese Witherspoon auditioned for Cher in Clueless, but wasn’t cast.